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| SILVA,ALESSANDRO A.L.S.; FRANCO,ADEMIR; FERNANDES,ÂNGELA; COSTA,CLAUDIO; BARBOSA,JORGE S.; WESTPHALEN,FERNANDO H.. |
| ABSTRACT The present study aimed to assess the accuracy of linear measurements performed with two software packages in multislice (MSCT) and cone beam (CBCT) computed tomography (CT) images. The sample consisted of 10 human mandibles marked standardly 8 times with metallic orthodontic wires. The mandibles underwent both MSCT and CBCT scanning and were measured linearly and digitally with two software packages, namely Studio 3.1® (Anne Solutions®, SP, Brazil) (ST) and Implant Viewer 2.817® (Anne Solutions®, SP, Brazil) (IV). The linear measurements were the mandibular height (MH) and width (MW), and the distance from the alveolar ridge to the mandibular canal (AC). To validate the measurements, the mandibles were sectioned in the marked regions and measured... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Computed tomography; Dental implant; Morphology; Radiology. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000602865 |
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| BOAVENTURA,MARIA AMÉLIA D.; XAVIER,LAURA F.W.; VIEIRA,HENRIETE S.; TAKAHASHI,JACQUELINE A.; NASCIMENTO JUNIOR,WILTON J.D.; ARAUJO,TAMIRES P.; COELHO,AMANDA C.S.. |
| ABSTRACT Thirteen natural products derivatives of hydroxyl amide class, three described for the first time, were synthesized by reaction of three indole acids and 3,4,5-trimethoxybenzoic acid with six different amino alcohols in the presence of triphenylphosphine and N-bromosuccinimide. The derivatives were tested against the Gram (+) bacteria Staphylococcus aureus and Bacillus cereus, Gram (-) Pseudomonas aeruginosa and Escherichia coli, besides the yeast Candida albicans. One of the compounds (7) was selectively active against C. albicans (91.3 ± 0.49% inhibition) showing a great potential as a new drug lead, since it was more active than the positive control, miconazole (88.7 ± 2.41% inhibition). Regarding bacterial inhibition, compounds demonstrated... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Acetylcholinesterase inhibition antimicrobial activity indole acid derivatives 3; 4; 5-trimethoxybenzoic acid derivatives. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000501945 |
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| DIAS,CINTIA M.M.; ROSA,LUIZ P.; GOMEZ,JOSE M.A.; D’AVIGNON,ALEXANDRE. |
| ABSTRACT Sanitation (which includes national public policies for drinking water, sewage services and waste management) is precarious in Brazil and therefore poses a challenge to a range of actors. Poor sanitation impacts public health, education, the environment, and daily life. Globally, it emits increasing greenhouse gases. Universalization of any major public service appears difficult, if not impossible; however, Brazil’s program to universalize access to electricity proves the opposite, as will be shown in this paper. By describing the successful implementation of electricity for everyone, we show that planned public efforts, coordinated with private initiatives and local communities, have worked, and the same can be achieved for the sanitation... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Solid Waste (SW); Water; Sewage; Sanitation; Greenhouse gases; Sustainable Development Goals (SDGs). |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000401337 |
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| Carvalho,Cristiane S.; Melo,Edésio J.T.. |
| Toxoplasma gondii multiplies within parasitophorous vacuole that is not recognized by the primary no oxidative defense of host cells, mainly represented by the fusion with acidic organelles. Recent studies have already shown that hydroxyurea arrested the intracellular parasites leading to its destruction. In the present work we investigated the cellular mechanism involved in the destruction of intracellular Toxoplasma gondii. Fluorescent vital stains were used in order to observe possible acidification of parasitophorous vacuole-containing Toxoplasma gondii in presence of hydroxyurea. Vero cells infected with tachyzoites were treated with hydroxyurea for 12, 24 or 48 hours. Fluorescence, indicative of acidification, was observed in the parasitophorous... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hydroxyurea; Toxoplasma gondii; Parasitophorous vacuole. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652006000300008 |
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| Chiglino,Leticia; Gaucher,Claudio; Sial,Alcides N.; Ferreira,Valderez P.. |
| We report for the first time the occurrence of organic-walled microfossils in Ediacaran limestones and marls of the Frecheirinha Formation, Ubajara Group, and the first Precambrian acritarchs so far reported for northeastern Brazil. The assemblage of the Frecheirinha Formation represents a low-diversity microflora comprising Leiosphaeridia, Lophosphaeridium and subordinated Bavlinella (=Sphaerocongregus). Their thermal alteration index (TAI) between 4+ and 5, suggests metamorphic temperatures exceeding 200-250°C. Higher temperatures are probably related to intruding granitic plutons (Meruoca, Mucambo). Reported δ13C values of carbonates of -3.5 ‰ VPDB (Vienna-Peedee Belemnite) at the base, passing up section into a positive plateau of up to +3.7 ‰, and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Acritarchs; Ediacaran; Neoproterozoic; Northeastern Brazil. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000200635 |
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| Oliva,Maria Luiza V.; Sampaio,Misako U.. |
| Obtained from leguminous seeds, various plant proteins inhibit animal proteinases, including human, and can be considered for the development of compounds with biological activity. Inhibitors from the Bowman-Birk and plant Kunitz-type family have been characterized by proteinase specificity, primary structure and reactive site. Our group mostly studies the genus Bauhinia, mainly the species bauhinioides, rufa, ungulata and variegata. In some species, more than one inhibitor was characterized, exhibiting different properties. Although proteins from this group share high structural similarity, they present differences in proteinase inhibition, explored in studies using diverse biological models. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bowman-Birk; Chymotrypsin; Kunitz inhibitors; Plasma kallikrein; Primary structure; Trypsin. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000300023 |
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| SANTOS,NEYLIANE F.G. DOS; SILVA,RAFAEL F.; PINTO,MARCELA M.P.L.; SILVA,EDVANE B. DA; TASAT,DEBORAH R.; AMARAL,ADEMIR. |
| ABSTRACT Several molecules and events involved in cell response to radiation-induced damage have been investigated towards a personalized radiotherapy. Considering the importance of active caspase-3 in the proteolytic cascade that ensures radiation-induced apoptosis execution, this research was designed to evaluate the expression levels of this protein as a bioindicator of individual radiosensitivity. Peripheral blood samples of 10 healthy individuals were gamma-irradiated (cobalt-60 source) with 1, 2 and 4 Gy (control: non-irradiated samples), and active caspase-3 expression levels were measured in lymphocytes, by flow cytometry, ex vivo and after different times of in vitro incubation (24, 48 and 72 hours). Short-term incubation of 24 h was the most... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Active caspase-3; Apoptosis; Flow cytometry; Ionizing radiation; Lymphocytes. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000200649 |
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| Bhuiyan,Mohammad A.S.; Zijie,Yeoh; Yu,Jae S.; Reaz,Mamun B.I.; Kamal,Noorfazila; Chang,Tae G.. |
| Modern Radio Frequency (RF) transceivers cannot be imagined without high-performance (Transmit/Receive) T/R switch. Available T/R switches suffer mainly due to the lack of good trade-off among the performance parameters, where high isolation and low insertion loss are very essential. In this study, a T/R switch with high isolation and low insertion loss performance has been designed by using Silterra 0.13µm CMOS process for 2.4GHz ISM band RF transceivers. Transistor aspect ratio optimization, proper gate bias resistance, resistive body floating and active inductor-based parallel resonance techniques have been implemented to achieve better trade-off. The proposed T/R switch exhibits 0.85dB insertion loss and 45.17dB isolation in both transmit and receive... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Active inductor; CMOS; ISM band; T/r switch; Transceiver. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000301089 |
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| MARINHO,ANDREY M.R.; MARINHO,PATRÍCIA S.B.; SANTOS,LOURIVALDO S.; RODRIGUES FILHO,EDSON; FERREIRA,IZABEL C.P.. |
| In this work we are reporting the isolation by classical methods of chromatography of six polyketides from Penicillium herquei. The compounds citreorosein ( 1) , emodin ( 2) , janthinone ( 3) , citrinin ( 4) , citrinin H1 ( 5) and dicitrinol ( 6) were identified by spectral methods of 1D and 2D NMR and MS. Compounds 1, 2 and 3 were tested against promastigotes forms of Leishmania brasiliensis and 1 and 2 were also assayed against Escherichia coli, Pseudomonas aeruginosa and Bacillus subtilis and showed good activity. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Polyketides; Biological assay; P. herquei. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000300909 |
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| ORSI,RICARDO O.; SANTOS,VIVIAN G. DOS; PEZZATO,LUIZ E.; CARVALHO,PEDRO L.P.F. DE; TEIXEIRA,CAROLINE P.; FREITAS,JAKELINE M.A.; PADOVANI,CARLOS R.; SARTORI,MARIA M.P.; BARROS,MARGARIDA M.. |
| ABSTRACT The effect of the ethanolic extract of propolis (EEP) on Aeromonas hydrophila was analyzed by determination of minimum inhibitory concentration (MIC). Then, the effects of crude propolis powder (CPP) on growth, hemato-immune parameters of the Nile tilapia, as well as its effects on resistance to A. hydrophila challenge were investigated. The CPP (0.5, 1.0, 1.5, 2.0, 2.5 and 3.0%) was added to the diet of 280 Nile tilapia (50.0 ± 5.7 g fish-1). Hemato-immune parameters were analyzed before and after the bacterial challenge. Red blood cell, hematocrit, hemoglobin, mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC), and hydrogen peroxide (H2O2) and nitric oxide (NO) were evaluated. The MIC of the EEP was 13% (v/v) with a... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Health; Hematology; Immunology; Oreochromis niloticus; Propolis; Stress. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000401785 |
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| TEODORAK,BRENA P.; FERREIRA,GABRIELA K.; SCAINI,GISELLI; WESSLER,LETÍCIA B.; HEYLMANN,ALEXANDRA S.; DEROZA,PEDRO; VALVASSORI,SAMIRA S.; ZUGNO,ALEXANDRA I.; QUEVEDO,JOÃO; STRECK,EMILIO L.. |
| Fenproporex is the second most commonly amphetamine-based anorectic consumed worldwide; this drug is rapidly converted into amphetamine, in vivo, and acts by increasing dopamine levels in the synaptic cleft. Considering that fenproporex effects on the central nervous system are still poorly known and that acetylcholinesterase is a regulatory enzyme which is involved in cholinergic synapses and may indirectly modulate the release of dopamine, the present study investigated the effects of acute administration of fenproporex on acetylcholinesterase activity in brain of young rats. Young male Wistar rats received a single injection of fenproporex (6.25, 12.5 or 25mg/kg i.p.) or vehicle (2% Tween 80). Two hours after the injection, the rats were killed by... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Acetylcholinesterase; Amphetamine; Dopamine; Fenproporex. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000301389 |
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| BARBOSA,HUMBERTO M.; NASCIMENTO,JAILSON N. DO; ARAÚJO,THIAGO A.S.; DUARTE,FILIPE S.; ALBUQUERQUE,ULYSSES P.; VIEIRA,JEYMESSON R.C.; SANTANA,EDSON R.B. DE; YARA,RICARDO; LIMA,CLÁUDIA S.A.; GOMES,DAYANE A.; LIRA,EDUARDO C.. |
| ABSTRACT Spondias tuberosa Arruda, popularly named as umbu, is native from savanna-like vegetation and widely used for medicinal purposes, however, the toxicological profile is not available yet. This study evaluated the phytochemical profile and acute toxicity and citoxicity of Ethanolic Extract of Spondias tuberosa Arruda Bark (EEStb) in hematological, biochemical and histopathological parameters. Female Wistar rats were divided into: control (C) and animal treated single doses of 300mg/Kg (EEStb300) or 2.000mg/kg body weight (ESStb2.000) of the EEStb. After 24 hours and 14 days from gavage, the behavior, hematological, biochemical and histopathological parameters were assayed. Cytotoxicity effect was evaluated on HEp-2 cell lines. Neither EEStb300 nor... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Acute toxicity; Cytotoxicity; Phytomedicine; Safety; Spondias tuberosa Arruda; Toxicology. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000501993 |
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| Registros recuperados: 2.719 | |
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